Among the 467 336 participants of the European Prospective Investigation into Cancer and Nutrition cohort, 275 develop a HCC and 257 a cholangiocarcinoma. Vigorous physical activity (> 2 hours per week) was associated with a decreased risk of HCC (HR = 0.50 CI95% 0.33-0.76) potentially mediated by a decreased of obesity.

(Baumeister SE et al. – Journal of Hepatology, 21 December 2018)

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