Authors analysed the immune microenvironment in 919 regions from 158 hepatocellular carcinomas, and identified three distinct immune-subtypes. Intratumor heterogeneity among immune subtypes was observed in 50% of cases, possibly reflecting the multistep nature of HCC carcinogenesis.

(Kurebayashi Y et al. – Hepatology, 30 March 2018)

Read more